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Science Friday > Archives > 1998 > September > September 25, 1998:

Hour Two:
Framingham Heart Study

In 1948, a group of scientists began a long-term medical study in a small town in Massachusetts. Fifty years later, their work has yielded an amazing amount of information about heart conditions and the risk factors that can lead to them. In this segment of Science Friday, we'll take a look back at the groundbreaking Framingham Heart Study and talk about the contributions it has made to medicine over the last fifty years.


During its first phase, the Framingham Heart Study collected data from over 5000 residents of the town of Framingham, MA. Participants, both men and women, volunteered for regular physical exams during which they submitted to dozens of medical tests and answered detailed questions about their personal habits. Then the researchers sat back and watched the health of the volunteers, looking for connections between the health of the volunteers' circulatory systems and the data that had been collected.

Over the past five decades, researchers involved in the study discovered many of the risk factors for heart disease that doctors now take for granted - connections between fat consumption and cholesterol levels, between smoking and heart disease, and between weight and blood pressure, among many others. Data from the Framingham residents have been shared with other research projects as well, providing information about conditions from Alzheimer's to osteoporosis. A second phase of the study, begun in 1971, enrolled over 5000 descendants of the original volunteers and continues to track them today. How was the study done, and what had it taught us? Join us for this segment of Science Friday to find out.

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Guests:
Daniel Levy, M.D.
Director, Framingham Heart Study
National Heart, Lung, and Blood Institute
Framingham, MA

Peter Buttrick, M.D.
Professor of Medicine
Chief of Cardiology
University of Illinois at Chicago
Chicago, IL

Rick Lofton
Professor of Medicine and Genetics
Yale University School of Medicine
New Haven, CT

Books/Articles Discussed:

Related Links:
National Heart Lung and Blood Institute's Framingham info
American Heart Association
American College of Cardiology
Heart Information Network


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