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Science Friday > Archives > 2000 > June > June 30, 2000: 

Hour One: Malaria / Bird-Dino Debate

There are an estimated 300-500 million cases of malaria worldwide each year, and each year the disease claims over a million victims. Malaria kills more people than any other communicable disease except tuberculosis. However, perhaps because over 90% of modern malaria cases are in sub-Saharan Africa, the mosquito-borne illness is not a major topic of discussion in the U.S --even though, until recently, malaria was endemic in the eastern United States.

Blood-feeding Anopheles gambiae
mosquito (CDC/James D. Gathany)

In the past week, however, several research efforts have been reported that may, down the road, bring some new weapons in the war against malaria. This week, researchers report in the journal Science that they have successfully grown the parasites responsible for malaria in fruit flies. They hope that their research will help scientists study the mechanism that allows or prevents insects from carrying and transmitting the malaria parasite.

Last week, a team of scientists reported that they had been able to genetically modify a mosquito. Their test, which involved engineering the mosquitoes to produce a fluorescent green protein, raises the possibility that mosquitoes could be engineered to no longer be able to carry the malaria parasite. Efforts to target the parasite through vaccines in humans have so far had only limited success.

On this hour of Science Friday, we'll talk about ongoing research into ways to prevent and cure malaria. We'll also take a closer look at the long-running debate over whether birds evolved from dinosaurs, or both evolved separately from a common ancestor. Fossilized feathers from a 220-million-year- old fossil of Longisquama insignis found in central Asia in the 1970's may help shed some light on the debate. We'll talk with one of the researchers studying the remains.

Disease, dinosaurs, and your questions - call us at 1-800-989-8255.


The oldest feathers?
(image Oregon State University)

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Guests:

David Schneider
Whitehead Fellow
Whitehead Institute for Biomedical Research
Massachusetts Institute of Technology
Cambridge, Massachusetts

Craig J. Coates
Assistant Professor, Entomology
Center for Advanced Invertebrate Molecular Science
Texas A&M University
College Station, Texas

Lawrence Martin
Paleontologist
Curator of Vertebrate Paleontology
Natural History Museum
University of Kansas
Lawrence, Kansas

Books/Articles Discussed:

 

"Taking Wing: Archaeopteryx and the Evolution of Bird Flight" by Pat Shipman. Simon and Schuster, 1998.

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Related Links: 

Malaria Foundation International
Mosquito Genomics WWW
World Health Organization/OMS: Malaria
African Malaria Vaccine Testing Network
NCBI - Malaria Genetics & Genomics
American Society of Tropical Medicine and Hygiene
MALARIA - DIAGNOSIS, PROPHYLAXIS, TREATMENT
SciFri: April 18, 1997, Hour One:Malaria
SciFri: September 3, 1999, Hour 1: DDT and Malaria/Brainy Mice
 
SciFri: June 26, 1998, Hour 1: Birds from Dinosaurs?
SciFri: October 18, 1996, Hour Two:Vertebrate Paleontology

Produced By: Annette Heist and Naomi Lubick
Web Producer: Charles Bergquist

 

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