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Science Friday > Archives > 2001 > April > April 20, 2001:

Hour Two: Biotechnology and Endangered Species

Earlier this year, the company Advanced Cell Technology announced that it had cloned an endangered animal -- a gaur, an ox-like animal found in tropical woodlands in India, Indochina, and the Malay Peninsula.

The cells used to create the clone (which the researchers named "Noah") were taken from a skin sample taken from a deceased gaur during an autopsy. Genetic material from the gaur cells was implanted into an egg taken from a cow, which was then carried to term in a regular female cow. Noah died within 48 hours of birth from dysentery, which scientists said was unrelated to the cloning process. The company is currently investigating cloning pandas, using black bears as hosts.


The birth of "Noah," a cloned gaur, January 2001.
Noah died soon after birth of an illness that
scientists believe to be a dysentery-like infection
unrelated to the cloning process.
(Advanced Cell Technology photo)
The birth raised the profile of the use of biotechnology in conservation efforts -- but biotech techniques for working with endangered species aren't just limited to cloning. Many researchers are using genetic samples to study the distribution of species, and track the interrelations between one cluster of animals and another. Such studies can help to prevent excessive interbreeding among small groups of animals.

Florida Panther.
(USFWS photo/Don Pfitzer)
Genetic studies were also key to an effort to help the endangered Florida panther. As populations of the large cat dwindled, the remaining animals became more and more inbred. Conservationists discovered through genetic tests that the Florida panthers were closely related to Texas cougars, and had previously interbred. By introducing some of the cougars into the Florida panther breeding pool, the scientists were able to increase the genetic diversity of the species, producing a more healthy population.

Some conservation scientists are using biotechnology to monitor trade in endangered species -- and some are even looking into the possibility of producing desirable animal products through artificial means, decreasing the threat to endangered species. What other tools might be available to researchers in the coming years? We'll talk about it. Call in with your questions and comments at 1-800-989-8255, and share your opinions online in our Listeners' Lounge (registration required)

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Guests:
Joshua Ginsberg
Director for Asia Programs
Wildlife Conservation Society
New York, New York

Betsy Dresser
Senior Vice President of Research
Audubon Nature Institute
New Orleans, Louisiana

Stephen O'Brien
Chief, Laboratory of Genomic Diversity
Frederick Cancer Research and Development Center
National Cancer Institute, National Institutes of Health
Frederick, Maryland

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Related Links:
Scientific American: Feature Article: Cloning Noah's Ark: November 2000
Genome Resource Banks: Living collections for biodiversity conservation
Florida panther, Links, Endangered Species: U.S. Fish & Wildlife Service
San Diego Zoo: CRES
Wired: Let's Go to the DNA Zoo!
Advanced Cell Technology
Smithsonian "NOAHS" Network (New Opportunities in Animal Health Sciences)
Smithsonian Genome Resource Bank
National Fish and Wildlife Forensics Laboratory
ABCNEWS.com : Cloning Endangered Species
Cloning a Comeback? (washingtonpost.com)

This segment produced by: Annette Heist
Web producer: Charles Bergquist

 

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