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Science Friday > Archives > 2001 > March > March 16, 2001:

Hour Two: Proteomics

You've heard about the human genome -- but what about the human proteome?

The genome is the blueprint for the human body. In all that DNA hide the codes for making the real workhorses of biology -- the proteins. Proteins are the hormones, enzymes, regulators, and chemical messengers that guide, in one way or another, all of your body's most basic processes. They also play a crucial role in most diseases. Now, scientists are trying to use what they've learned from studying the human genome to study the proteome -- turning the blueprint into n understandable list of building materials and their uses.


This protein, known as OspC,
plays a role in Lyme Disease infection.
(Brookhaven National Laboratory image)

In this hour, we'll take a look at the rapidly growing science of proteomics. How are scientists cataloguing all the proteins in the body -- and how will that information be useful? Call in with your questions and comments at 1-800-989-8255, and share your opinions online in our Listeners' Lounge (registration required)

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Guests:
William Haseltine
Chairman, Chief Executive Officer
Human Genome Sciences, Inc.
Rockville, Maryland

Joshua Labaer
Director, Institute of Proteomics
Harvard Medical School
Medical Oncologist
Dana Farber Cancer Institute
Cambridge, Massachusetts

Vijay Pande
Assistant Professor, Chemistry and Structural Biology
Stanford University
Stanford, California

Books/Articles Discussed:

 

 

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Related Links:
TIME Magazine: The Next Frontier: Proteomics
Chemical & Engineering News: Proteomics
ExPASy - Tools
genome gateway > post-genomics > proteomics in action
Harvard Institute of Proteomics
Incyte: Proteomics Tour
Folding@home
Genome@home

This segment produced by: Annette Heist
Web Producer: Charles Bergquist

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Web producer: Charles Bergquist

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