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Science Friday > Archives > 2002 > April > April 5, 2002:

Hour One: Gene-Based Medicine

One often-stated goal of the Human Genome Project was to provide medical researchers with information that would help them create better medications. This week, scientists at the University of Washington reported in the Journal of the American Medical Association that people with a certain gene are more likely to have a bad reaction to a commonly prescribed blood thinner than people without the gene.

In this hour, we'll take a look at the latest developments in gene-based medicine. How can your genetic information be used to make diagnosis easier and treatment better? Plus, genetic news in another field -- rice.

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Guests:
Rod Wing
Director, Clemson University Genome Institute
Professor
Clemson University
Clemson, South Carolina

Robert Tepper
Chief Scientific Officer
Executive Vice President of Drug Discovery
Millennium Pharmaceuticals, Incorporated
Cambridge, Massachusetts

David Veenstra
Assistant Professor, School of Pharmacy
University of Washington
Seattle, Washington

Janet Warrington
Senior Director, Health Management Research
Affymetrix, Incorporated
Santa Clara, California

Books/Articles Discussed:

 
 
Association Between CYP2C9 Genetic Variants and Anticoagulation-Related Outcomes During Warfarin Therapy (JAMA)

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Related Links:
UW study links gene to success of a treatment for high blood pressure
Study shows genetic variants put some patients at risk for dangerous drug reactions Pharmacogenomics: Medicine and the New Genetics
C&EN: COVER STORY - PHARMACOGENOMICS
Pharmacogenomics: The Promise of Personalized Medicine - A Review by: Laviero Mancinelli, Maureen Cronin, Wolfgang Sadee
Pharmacogenomics:  A Public Health Perspective Editorial
PhRMA Genomics: A Global Resource

This segment produced by: Annette Heist


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