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Science
Friday > Archives > 2002 > August > August 16, 2002:
Hour One: Cows and
Antibodies / Alzheimer's Update
Researchers reported this
week that elderly people with symptoms of depression may be more likely
to develop Alzheimer' s disease than older people who aren't depressed.
. Although it's a common affliction -- 4 million Americans have Alzheimer's
disease, 19 million Americans have a family member with Alzheimer's,
and 37 million Americans know someone with the disease -- scientists
still have a long way to go just to understand all of the complex
factors leading to Alzheimer's. And while there are drugs that can
ease the symptoms temporarily, preventing it completely is still beyond
medical science. In this hour, we'll talk about the latest Alzheimer's
research, including current treatment and diagnosis
Plus, scientists report that they have created cloned cows that produce
human antibodies. Using genetic engineering, the cows were made to
express a mixture of human antibodies (known as immune globulin, immunoglobulin
or gamma globulin) used to treat immunodeficient humans. Will this
be a new way to produce drugs?
Call in with your comments and questions at 1-800-989-8255, and share
your opinions online in our Listeners'
Lounge (registration
required).
Guests:
James Robl
President and Chief Scientific Officer
Hematech
Westport, Connecticut
Robert Wilson
Professor, Neuropsychology
Rush Alzheimer's Disease
Center
Rush-Presbyterian-St. Luke's Medical
Center
Chicago, Illinois
Douglas Galasko
Professor, Department
of Neurosciences
University of California, San Diego
Staff Physician, San
Diego VA Medical Center
San Diego, California
Books/Articles Discussed:
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"Depressive symptoms, cognitive decline, and risk of AD
in older persons" by R.S. Wilson, PhD et al. NEUROLOGY
2002;59:364-370.
"Cloned transchromosomic calves producing human immunoglobulin"
by James M. Robl et al. Nature Biotechnology. Published online:
12 August 2002, doi:10.1038/nbt727.
(find
more SciFri books here)
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Related Links:
Alzheimer's
Disease Education and Referral (ADEAR Center)
Alzheimer's
Disease Clinical Trials Database
National
Institute on Aging - NIA
Alzforum:
Alzheimer Research Forum Home
AARP
Webplace | Life Answers Index
Welcome
to the Alzheimer's Association
N
C H S - FASTATS - Alzheimer's Disease
MEDLINEplus:
Alzheimer's Disease
NINDS
Alzheimer's Disease Information Page
NIH
Funded Alzheimer's Research (search)
ClinicalTrials.gov
Charlton
Heston Reveals He May Have Alzheimer's (washingtonpost.com)
BBC
NEWS | Health | Medical notes | A-B | Alzheimer's disease
Argus
Leader - Cows could increase vaccine supply
Cloned
cows make human antibodies
ABCNEWS.com
: Cloned Cows Generate Human Antibodies
BBC
NEWS | Science/Nature | Cows born with human DNA
Hematech
This segment produced by Karin
Vergoth and Dorothy Lam
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