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Science Friday > Archives > 2003 > July
> July 11, 2003:
Hour Two: Chromosome 7 / J. Michael Bishop - 'How to Win the Nobel Prize'
Researchers this week reported that they have completed the sequencing
of chromosome 7 in the human genome. It's the largest of the chromosomes
sequenced so far, and scientists believe that it contains genetic
code with links to deafness, cystic fibrosis, B-cell lymphoma and
other cancers. The chromosome has chromosome has about 1,150 genes
and 940 'pseudogenes,' regions that appear similar to genes but are
inactivated for some reason. We'll talk about the project to decode
chromosome 7, and what it might mean for biological and medical research.
Then, we'll turn our attention to past ground-breaking biological
science, and a conversation with J. Michael Bishop, co-winner of the
1989 Nobel Prize in Physiology or Medicine. Bishop shared the award
with Harold Varmus "for their discovery of the cellular origin of
retroviral oncogenes." The work has helped shape scientists' understanding
of mechanisms for cancer tumor development. We'll talk with Bishop
about his work, his life in science since then, and his new book,
"How to Win the Nobel Prize."
Call in with your questions and comments at 1-800-989-8255 (3-4 Eastern),
and share your opinions online in our Listeners' Lounge (registration required).
Guests:
Richard Wilson
Director, Genome Sequencing Center
Washington University School
of Medicine
St. Louis, Missouri
J. Michael Bishop, M.D.
Author,
"How to Win the Nobel Prize: An Unexpected Life in Science" (Harvard
University Press, 2003)
Chancellor
University of California San Francisco
San Francisco, California
Books/Articles Discussed:
Related Links:
Human
Chromosome 7
The
Chromosome 7 Project
National
Human Genome Research Institute - Genome Researchers Analyze Chromosome
7
- WU
team helps finish analysis of important chromosome
Scientists'
Map of Chromosome 7 , May Help Study of Diseases
- J.
Michael Bishop - Nobel Lecture
Medicine
1989
PBS
- The Nobel : Visions of Our Century
J.
Michael Bishop
This segment produced by Karin
Vergoth
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