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Proteins are crucial for life. They’re made of amino acids that “fold” into millions of different shapes. And depending on their structure, they do radically different things in our cells. For a long time, predicting those shapes for research was considered a grand biological challenge.
But in 2020, Google’s AI lab DeepMind released Alphafold, a tool that was able to accurately predict many of the structures necessary for understanding biological mechanisms in a matter of minutes. In 2024, the Alphafold team was awarded a Nobel Prize in chemistry for the advance.
Five years later after its release, Host Ira Flatow checks in on the state of that tech and how it’s being used in health research with John Jumper, one of the lead scientists responsible for developing Alphafold.
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Segment Guests
John Jumper
John Jumper is a scientist at Google DeepMind and a co-recipient of the 2024 Nobel Prize in chemistry.
Segment Transcript
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Meet the Producers and Host
About Dee Peterschmidt
Dee Peterschmidt is a producer, host of the podcast Universe of Art, and composes music for Science Friday’s podcasts. Their D&D character is a clumsy bard named Chip Chap Chopman.
About Ira Flatow
Ira Flatow is the founder and host of Science Friday. His green thumb has revived many an office plant at death’s door.