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Congratulations! You’ve learned some neuroscience basics, and hopefully had some fun with the Hack Your Brain puzzles along the way. Did you find them challenging, or even a little stressful? That’s ok! Stress can increase motivation and engagement, especially with games and puzzles. A good puzzle is challenging without being so difficult you want to give up. Of course, you may be wondering if there is a reward for all your hard work and perseverance. Well, there is!

Did you know you have reward centers in your brain? You do! Think about when you solved a Hack Your Brain puzzle or completed one of the challenges. Perhaps you got a high-five from a friend or a compliment from your teacher. How did that make you feel?

When your brain associates a stimulus or event with a positive outcome, it perceives that experience as a reward. In response, your brain releases endorphins. Endorphins are hormones that act as neurotransmitters, or messengers in your brain, specifically in the reward centers. The release of endorphins can improve your mental health and reduce your stress levels.

Your brain also releases another neurotransmitter called dopamine. Dopamine helps regulate your mood and improves motivation. When you do something pleasurable, like eating a cake, your brain releases dopamine, a “feel-good” hormone that can motivate you to continue or repeat that activity.

Rewards help with learning. If you have ever trained a pet, especially a dog, you know that you may give it a reward—such as a tasty treat, a pat on the head, or positive words—when the dog completes a desirable behavior, like sitting on command. During initial training, trainers reward dogs very frequently. This creates an association between the reward and the behavior, a practice known as positive reinforcement. Over time, trainers reduce the reward frequency and vary when the dog gets rewarded. Because the dog doesn’t know exactly when to expect the treat, it will keep responding, knowing that eventually it will get a reward, even if that doesn’t occur every time it does the desirable behavior.

This may work on some humans, too. For example, when you defeat monsters in your favorite video game, they don’t always drop treasure. However, you know they might reward you occasionally, so you keep playing!

The reward systems in our brains can have a downside, though. While the release of endorphins and dopamine can lead to learned positive behaviors, like eating healthy food or exercising, that same system can also contribute to negative behaviors, like scrolling on your phone rather than falling asleep, or playing video games for so long that you neglect your schoolwork! Your reward system is very active during adolescence, so it’s important to find balance and know when to take a break. Otherwise, a dysregulated reward system can lead to mental health problems and even addiction.

So, if rewards can help us learn, and games provide rewards, can games help us learn? The short answer is: yes. Games can be motivating, encourage participation, and make some types of learning more engaging. For example, in Hack Your Brain, Science Friday used games and puzzles to motivate you to learn about neuroscience. Cool, right?

Researchers have used our reaction to rewards to develop games that encourage people to do science. Try one of the game-based neuroscience projects below and help scientists understand more about how the brain works. As a bonus, if you do a project during the month of April, you can contribute to SciStarter’s One Million Acts of Science by joining people around the world who are participating in scientific research—just like you!

• EyeWire: This project uses a puzzle-style game where players map nerve cells in the eye using a type of high-tech, 3D coloring book. By mapping nerve connections, EyeWire researchers can gain insights into how neurons process information and detect motion.
• The Happiness Project: Using simple games, this project’s goal is to develop mathematical equations that explain how humans make decisions. The researchers hope this will help them understand the relationship between happiness and behavior, which may lead to new mental health treatments.
• Neureka: Through games, quizzes, and surveys, Neuraka aims to improve mental health by understanding how mood, behavior, and environment interact. Using the phone app, you can participate in different challenges. Researchers use the data collected to understand how the brain works, while you get to build better habits. Note: This project is for those 18 and up.
• The Online Memory Training Study: This NIH-funded study asks you to play games that present stimuli and activate your working memory. The entire program can be completed at home in about 11 days. The goal is to understand how memory training can lead to cognitive benefits. Note: This project is for those 18 and up.

Visit the SciStarter website for more gamified ways to level up your participation in science. Be sure to create an account to track your progress and report your “acts of science,” too! Want to learn more? Join Science Friday and SciStarter for a very special webinar on April 25th at 8 pm ET / 5 pm PT!

🔍 Hack Your Brain: You’re the Scientist!
Thursday, April 25, 8 pm ET / 5 pm PT
Dive into the thrilling world of neuroscience with our upcoming webinar with SciStarter and Citizen Science Month! Join groundbreaking projects like Neureka, where you can play games and share your feelings to understand mental health evolution, and the Online Memory Training Study, where you’ll engage in memory-boosting exercises and cognitive tests from home. Be a part of cutting-edge research and uncover the mysteries of the brain. Sign up now and contribute to exciting scientific discoveries!

RSVP for April 25!

The team at Science Friday hopes you enjoyed the Hack Your Brain escape room adventure and learned valuable information about how your brain processes information and memories! How can you use what you’ve learned to make your life better? Take a moment to reflect on these lessons, write down your thoughts, and share your experience with a friend, trusted adult, or younger sibling. Science Friday would love to hear from you as well. Use this form to share one way you plan to use your new knowledge of neuroscience to improve your life. If you do, we’ll send you some free stickers as a reward!

Share Your Thoughts!

This activity and puzzle are part of the Hack Your Brain neuroscience escape room. Join the newsletter to get the full five-day experience.

Here are some great resources for you to check out!

• Do you want to make your own game? You can! Try free coding platforms like Scratch or MakeCode to create your own video games. Or try designing your own board game.
• Continue the Hack Your Brain fun with a coloring sheet, crossword puzzle, word search, maze, and fill in the blanks game.
• Addiction is a chronic disease of brain reward, learning, and motivation that can cause long-term changes in the dopamine system. Understanding how addiction works, and how to get help if you need it, can be an important part of living a healthy life.

MS-LS1-8 From Molecules to Organisms: Structures and Processes: Gather and synthesize information that sensory receptors respond to stimuli by sending messages to the brain for immediate behavior or storage as memories.

Special thanks to the Dana Foundation for funding Hack Your Brain.

Credits
Lesson by Svea Anderson
Neuroscience Consultation by Daisy Reyes
Game Design by Lucas Leprince
Illustration by Joy Ho
Puzzle Illustration by Fai Kosciolek
Developmental Editing by Sandy Roberts
Copyediting by Ariel Zych
Digital Production by Sandy Roberts