08/08/25

Lithium May Have A Role In Causing—And Treating—Alzheimer’s

The mechanisms behind Alzheimer’s disease have eluded scientists for decades. But a new breakthrough points to lithium as a possible explanation—not only does it occur naturally in the brain, but a deficiency causes dementia in mice. This research is one of thousands of projects that have lost funding due to President Trump’s cuts to the National Institutes of Health (NIH).

Host Ira Flatow speaks with Alzheimer’s researcher Bruce Yankner about this new finding, and then to epidemiologist Katelyn Jetelina and immunologist Elisabeth Marnik about the country’s “quiet engine of science,” the NIH.


Further Reading

  • Read Katelyn Jetelina’s Substack post about the dismantling of the NIH.

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Segment Guests

Bruce Yankner

Dr. Bruce Yankner is professor of genetics and neurology at Harvard Medical School in Boston, Massachusetts.

Katelyn Jetelina

Katelyn Jetelina is an adjunct professor in the UTHealth School of Public Health, and author of the Your Local Epidemiologist newsletter.

Elisabeth Marnik

Dr. Elisabeth Marnik is an immunologist and Director of Science Education & Outreach at the MDI Biological Laboratory in Bar Harbor, Maine.

Segment Transcript

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Meet the Producers and Host

About Kathleen Davis

Kathleen Davis is a producer and fill-in host at Science Friday, which means she spends her weeks researching, writing, editing, and sometimes talking into a microphone. She’s always eager to talk about freshwater lakes and Coney Island diners.

About Ira Flatow

Ira Flatow is the founder and host of Science FridayHis green thumb has revived many an office plant at death’s door.

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