09/16/2025

A Trailblazing Geneticist Reflects On Her Life And Work

It’s common knowledge that many diseases and conditions have some kind of genetic link. But that wasn’t always the case. In 1990, long before the Human Genome Project tied so many health issues to differences in genetics, researchers identified a gene called BRCA1. It was the first gene linked to a hereditary form of any common cancer. People with certain variants of BRCA1 stood a higher risk of developing breast and ovarian cancer than those without those mutations.  

Geneticist Mary-Claire King and her lab were the first to identify that gene. She joins Host Flora Lichtman to talk about her background, her research, and her approach to science.


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Segment Guests

Mary-Claire King

Dr. Mary-Claire King is professor of medical genetics and of genome sciences at the University of Washington in Seattle, Washington.

Segment Transcript

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Meet the Producers and Host

About Charles Bergquist

As Science Friday’s director and senior producer, Charles Bergquist channels the chaos of a live production studio into something sounding like a radio program. Favorite topics include planetary sciences, chemistry, materials, and shiny things with blinking lights.

About Flora Lichtman

Flora Lichtman is a host of Science Friday. In a previous life, she lived on a research ship where apertivi were served on the top deck, hoisted there via pulley by the ship’s chef.

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