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Perimenopause affects more than 4 billion people, but has historically been neglected by medicine. It’s the time before menopause when hormones start fluctuating wildly, leaving women with brain fog, hot flashes, dropping bone density, and mood changes. Thanks in part to social media, it’s more prominent in public discourse than it used to be.
But it’s not just awareness that’s blown up: It’s also the promise that you don’t have to suffer like those before you, thanks to hormone therapy. After decades of controversy over prescribing estradiol and progesterone due to concerns of increased breast cancer and heart disease risk, new research has many providers reconsidering their approach.
Joining Flora to sort out the science are reproductive endocrinologists Nanette Santoro and Genevieve Neal-Perry, who are both running some of the biggest long-term studies on perimenopause and the effects of hormone therapy.
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Segment Guests
Nanette Santoro
Dr. Nanette Santoro is a reproductive endocrinologist at the University of Colorado Anschutz and is the president of the Endocrine Society.
Genevieve Neal-Perry
Dr. Genevieve Neal-Perry is a reproductive endocrinologist and the OB-GYN department chair at the University of North Carolina at Chapel Hill.
Segment Transcript
The transcript is being processed. It will be available 2-3 days after this story’s publication date.
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About Dee Peterschmidt
Dee Peterschmidt is Science Friday’s audio production manager, hosted the podcast Universe of Art, and composes music for Science Friday’s podcasts. Their D&D character is a clumsy bard named Chip Chap Chopman.
About Flora Lichtman
Flora Lichtman is a host of Science Friday. In a previous life, she lived on a research ship where apertivi were served on the top deck, hoisted there via pulley by the ship’s chef.